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What is the difference between an allergy and an irritant reaction?
An allergic reaction (allergic contact dermatitis) involves the immune system and requires previous sensitisation — meaning the first exposure causes no reaction, but subsequent exposures trigger an immune response. An irritant reaction (irritant contact dermatitis) does not involve the immune system and can occur on first contact with a substance that is directly damaging to the skin, such as strong acids, detergents, or repeated wet work.
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What is patch testing and how does it work?
Patch testing is the gold standard investigation for contact allergic dermatitis. A series of standard allergens — typically 30–50 common chemical sensitisers — are applied to the back under adhesive chambers for 48 hours. The patches are then removed and the skin is read at 48 and 96 hours for positive reactions (localised redness, swelling, or blistering). Results identify which specific substances you are allergic to.
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How common are cosmetic allergies?
Cosmetic allergies are increasingly common. The most frequent culprits include fragrances, preservatives such as methylisothiazolinone (MI), nickel in jewellery or tools, hair dyes (particularly p-phenylenediamine), and certain plant extracts. Patch testing identifies the specific allergens, enabling targeted avoidance.
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Can a skin allergy appear for the first time after years of using a product?
Yes. Allergic sensitisation can develop at any point — even after years of uneventful use of the same product. This is because sensitisation builds over time with repeated exposure, and once the threshold is crossed, even small amounts of the allergen can trigger a reaction.
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What is chronic spontaneous urticaria?
Chronic spontaneous urticaria is urticaria that occurs daily or almost daily for more than six weeks without a consistently identifiable external trigger. It is not usually caused by a traditional allergy but rather by immune dysregulation. It is treated with non-sedating antihistamines and, for resistant cases, with omalizumab (an injectable biologic) under specialist supervision.
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When should I go to A&E for a skin reaction?
Seek emergency treatment immediately if a skin reaction is accompanied by swelling of the face, lips, tongue, or throat; difficulty breathing or swallowing; dizziness or collapse. These symptoms may indicate anaphylaxis, which is a life-threatening emergency.
Your Patient Journey
1. Your
Consultation
Your dermatologist will take a detailed history of your skin reactions — when they occur, what they look like, potential triggers, any products, foods, or medications involved, and your occupation and hobbies. The skin is examined and investigations including patch testing or blood tests may be arranged to identify the causative allergen.